Synthesis of a Vpr-Binding Derivative for Use as a Novel HIV-1 Inhibitor

The emergence of multidrug-resistant viruses compromises the efficacy of anti-human immunodeficiency virus type 1 (HIV-1) therapy and limits treatment options. Therefore, new targets that can be used to develop novel antiviral agents need to be identified. We previously identified a potential parent...

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Udgivet i:PLoS One
Main Authors: Hagiwara, Kyoji, Ishii, Hideki, Murakami, Tomoyuki, Takeshima, Shin-nosuke, Chutiwitoonchai, Nopporn, Kodama, Eiichi N., Kawaji, Kumi, Kondoh, Yasumitsu, Honda, Kaori, Osada, Hiroyuki, Tsunetsugu-Yokota, Yasuko, Suzuki, Masaaki, Aida, Yoko
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689350/
https://ncbi.nlm.nih.gov/pubmed/26701275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145573
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