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Identification of amino acid residues that determine the substrate specificity of mammalian membrane-bound front-end fatty acid desaturases

Membrane-bound desaturases are physiologically and industrially important enzymes that are involved in the production of diverse fatty acids such as polyunsaturated fatty acids and their derivatives. Here, we identified amino acid residues that determine the substrate specificity of rat Δ6 desaturas...

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Pubblicato in:J Lipid Res
Autori principali: Watanabe, Kenshi, Ohno, Makoto, Taguchi, Masahiro, Kawamoto, Seiji, Ono, Kazuhisa, Aki, Tsunehiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689341/
https://ncbi.nlm.nih.gov/pubmed/26590171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M064121
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