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Identification of amino acid residues that determine the substrate specificity of mammalian membrane-bound front-end fatty acid desaturases

Membrane-bound desaturases are physiologically and industrially important enzymes that are involved in the production of diverse fatty acids such as polyunsaturated fatty acids and their derivatives. Here, we identified amino acid residues that determine the substrate specificity of rat Δ6 desaturas...

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Bibliographic Details
Published in:J Lipid Res
Main Authors: Watanabe, Kenshi, Ohno, Makoto, Taguchi, Masahiro, Kawamoto, Seiji, Ono, Kazuhisa, Aki, Tsunehiro
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689341/
https://ncbi.nlm.nih.gov/pubmed/26590171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M064121
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