Modulation of Lipopolysaccharide Stimulated Nuclear Factor kappa B Mediated iNOS/NO Production by Bromelain in Rat Primary Microglial Cells

BACKGROUND: Microglial cells act as the sentinel of the central nervous system .They are involved in neuroprotection but are highly implicated in neurodegeneration of the aging brain. When over-activated, microglia release pro-inflammatory factors, such as nitric oxide (NO) and cytokines, which are...

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Bibliographic Details
Published in:Iran Biomed J
Main Authors: Abbasi Habashi, Soraya, Sabouni, Farzaneh, Moghimi, Ali, Ansari Majd, Saeed
Format: Artigo
Language:Inglês
Published: Pasteur Institute of Iran 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689280/
https://ncbi.nlm.nih.gov/pubmed/26459398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7508/ibj.2016.01.005
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