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Inhibiting effect of antisense oligonucleotides phosphorthioate on gene expression of TIMP-1 in rat liver fibrosis

AIM: To observe the inhibition of antisense oligonucleotides (asON) phosphorthioate to the tissue inhibitors metalloproteinase-1 (TIMP-1) gene and protein expression in the liver tissue of immunologically induced hepatic fibrosis rats. The possibility of reversing hepatic fibrosis through gene thera...

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Библиографические подробности
Опубликовано в: :World J Gastroenterol
Главные авторы: Nie, Qing-He, Cheng, Yong-Qian, Xie, Yu-Mei, Zhou, Yong-Xing, Cao, Yi-Zhan
Формат: Artigo
Язык:Inglês
Опубликовано: Baishideng Publishing Group Inc 2001
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688723/
https://ncbi.nlm.nih.gov/pubmed/11819791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v7.i3.363
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