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Simulation of Cl(−) Secretion in Epithelial Tissues: New Methodology Estimating Activity of Electro-Neutral Cl(−) Transporter

Transcellular Cl(−) secretion is, in general, mediated by two steps; (1) the entry step of Cl(−) into the cytosolic space from the basolateral space across the basolateral membrane by Cl(−) transporters, such as Na(+)-K(+)-2Cl(−) cotransporter (NKCC1, an isoform of NKCC), and (2) the releasing step...

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Bibliographic Details
Published in:Front Physiol
Main Authors: Sasamoto, Kouhei, Niisato, Naomi, Taruno, Akiyuki, Marunaka, Yoshinori
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688368/
https://ncbi.nlm.nih.gov/pubmed/26779025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00370
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