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Comprehensive review of BAP1 tumor predisposition syndrome with report of two new cases

The BRCA1-associated protein-1 (BAP1) tumor predisposition syndrome (BAP1-TPDS) is a recently identified hereditary cancer syndrome. Germline mutations in this tumor suppressor gene predispose families to the development of various malignancies. The molecular functions of the gene as well as the cli...

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Bibliographic Details
Published in:Clin Genet
Main Authors: Rai, K., Pilarski, R., Cebulla, C.M., Abdel-Rahman, M.H.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688243/
https://ncbi.nlm.nih.gov/pubmed/26096145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cge.12630
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