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TSPO in a Murine Model of Sandhoff Disease: Presymptomatic marker of neurodegeneration and disease pathophysiology

Translocator protein (18 kDa), formerly known as the peripheral benzodiazepine receptor (PBR), has been extensively used as a biomarker of active brain disease and neuroinflammation. TSPO expression increases dramatically in glial cells, particularly in microglia and astrocytes, as a result of brain...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Loth, Meredith, Choi, Judy, McGlothan, Jennifer L., Pletnikov, Mikhail V., Pomper, Martin G., Guilarte, Tomás R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688219/
https://ncbi.nlm.nih.gov/pubmed/26545928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.11.001
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