Fetal stress-mediated hypomethylation increases the brain susceptibility to hypoxic-ischemic injury in neonatal rats

BACKGROUND AND PURPOSE: Fetal hypoxia increases brain susceptibility to hypoxic-ischemic (HI) injury in neonatal rats. Yet mechanisms remain elusive. The present study tested the hypothesis that DNA hypomethylation plays a role in fetal stress-induced increase in neonatal HI brain injury. METHODS: P...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Li, Yong, Ma, Qingyi, Halavi, Shina, Concepcion, Katherine, Hartman, Richard E., Obenaus, Andre, Xiao, Daliao, Zhang, Lubo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688116/
https://ncbi.nlm.nih.gov/pubmed/26597542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.10.007
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