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What is the DNA repair defect underlying Fanconi anemia?
Fanconi anemia (FA) is a rare human genetic disease characterized by bone marrow failure, cancer predisposition, and genomic instability. It has been known for many years that FA patient-derived cells are exquisitely sensitive to DNA interstrand cross-linking agents such as cisplatin and mitomycin C...
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| Publicado no: | Curr Opin Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4688103/ https://ncbi.nlm.nih.gov/pubmed/26512453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2015.09.002 |
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