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Hybrid Polymeric Hydrogels via Peptide Nucleic Acid (PNA)/DNA Complexation

This work presents a new concept in hybrid hydrogel design. Synthetic water-soluble N-(2-hydroxypropyl)methacrylamide (HPMA) polymers grafted with multiple peptide nucleic acids (PNA) are crosslinked upon addition of the linker DNA. The self-assembly is mediated by the PNA–DNA complexation, which re...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Control Release
Egile Nagusiak: Chu, Te-Wei, Feng, Jiayue, Yang, Jiyuan, Kopeček, Jindřich
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688099/
https://ncbi.nlm.nih.gov/pubmed/26394062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.035
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