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Isotope-encoded Carboxyl Group Footprinting for Mass Spectrometry-based Protein Conformational Studies
We report an isotope-encoding method coupled with carboxyl-group footprinting to monitor protein conformational changes. The carboxyl groups of aspartic/glutamic acids and of the C-terminus of proteins can serve as reporters for protein conformational changes when labeled with glycine ethyl ester (G...
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| Publicado no: | J Am Soc Mass Spectrom |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4688080/ https://ncbi.nlm.nih.gov/pubmed/26384685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-015-1260-5 |
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