Overexpression of the Monocyte Chemokine CCL2 in Dorsal Root Ganglion Neurons Causes a Conditioning-Like Increase in Neurite Outgrowth and Does So via a STAT3 Dependent Mechanism

Neuroinflammation plays a critical role in the regeneration of peripheral nerves following axotomy. An injury to the sciatic nerve leads to significant macrophage accumulation in the L5 DRG, an effect not seen when the dorsal root is injured. We recently demonstrated that this accumulation around ax...

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Vydáno v:Exp Neurol
Hlavní autoři: Niemi, Jon P., DeFrancesco-Lisowitz, Alicia, Cregg, Jared, Howarth, Madeline, Zigmond, Richard E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688065/
https://ncbi.nlm.nih.gov/pubmed/26431741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.09.018
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