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Extended Release microparticle-in-gel Formulation of Octreotide: Effect of polymer type on acylation of Peptide during in vitro release

Polymeric microparticle(MPs)-in-gel formulations for extended delivery of octreotide were developed. We investigated influence of polymer composition on acylation of octreotide and kinetics of release during in vitro release from biodegradable polymeric formulations. Polycaprolactone (PCL), polylact...

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Detalhes bibliográficos
Publicado no:Int J Pharm
Main Authors: Vaishya, Ravi, Mandal, Abhirup, Patel, Sulabh, Mitra, Ashim K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688050/
https://ncbi.nlm.nih.gov/pubmed/26561725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2015.11.002
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