USP18 downregulation in peripheral blood mononuclear cells predicts nonresponse to interferon-based triple therapy in patients with chronic hepatitis C, genotype 1: a pilot study

BACKGROUND AND AIMS: Patients with advanced liver fibrosis owing to chronic hepatitis C virus genotype 1 represent a difficult-to-treat group even if a protease inhibitor is added to pegylated interferon alpha and ribavirin. Therefore, only patients with a high chance of cure should be treated with...

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Библиографические подробности
Опубликовано в: :Ther Clin Risk Manag
Главные авторы: Frankova, Sona, Jirsa, Milan, Merta, Dusan, Neroldova, Magdalena, Urbanek, Petr, Senkerikova, Renata, Spicak, Julius, Sperl, Jan
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2015
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687952/
https://ncbi.nlm.nih.gov/pubmed/26719699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S94010
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