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Protection against H5N1 Influenza Virus Induced by Matrix-M Adjuvanted Seasonal Virosomal Vaccine in Mice Requires Both Antibodies and T Cells

BACKGROUND: It remains important to develop the next generation of influenza vaccines that can provide protection against vaccine mismatched strains and to be prepared for potential pandemic outbreaks. To achieve this, the understanding of the immunological parameters that mediate such broad protect...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cox, Freek, Baart, Matthijs, Huizingh, Jeroen, Tolboom, Jeroen, Dekking, Liesbeth, Goudsmit, Jaap, Saeland, Eirikur, Radošević, Katarina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687931/
https://ncbi.nlm.nih.gov/pubmed/26696245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145243
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