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Trypanosome resistance to human innate immunity: targeting Achilles’ heel

Trypanosome lytic factors (TLFs) are powerful, naturally-occurring toxins in humans that provide sterile protection against infection by several African trypanosomes. These trypanocidal complexes predominantly enter the parasite by binding to the trypanosome haptoglobin/hemoglobin receptor (HpHbR),...

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Bibliographische Detailangaben
Veröffentlicht in:Trends Parasitol
Hauptverfasser: Stephens, Natalie A., Kieft, Rudo, MacLeod, Annette, Hajduk, Stephen L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687903/
https://ncbi.nlm.nih.gov/pubmed/23059119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pt.2012.09.002
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