A GFP-Tagged Gross Deletion on Chromosome 1 Causes Malignant Peripheral Nerve Sheath Tumors and Carcinomas in Zebrafish

Malignant peripheral nerve sheath tumors (MPNSTs) are highly aggressive soft-tissue sarcomas, characterized by complex karyotypes. The molecular bases of such malignancy are poorly understood and efficient targeted molecular therapies are currently lacking. Here we describe a novel zebrafish model o...

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Udgivet i:PLoS One
Main Authors: Astone, Matteo, Pizzi, Marco, Peron, Margherita, Domenichini, Alice, Guzzardo, Vincenza, Töchterle, Sonja, Tiso, Natascia, Rugge, Massimo, Meyer, Dirk, Argenton, Francesco, Vettori, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687860/
https://ncbi.nlm.nih.gov/pubmed/26695815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145178
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