A Peptide Derived from the HIV-1 gp120 Coreceptor-Binding Region Promotes Formation of PAP248-286 Amyloid Fibrils to Enhance HIV-1 Infection

BACKGROUND: Semen is a major vehicle for HIV transmission. Prostatic acid phosphatase (PAP) fragments, such as PAP248-286, in human semen can form amyloid fibrils to enhance HIV infection. Other endogenous or exogenous factors present during sexual intercourse have also been reported to promote the...

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Pubblicato in:PLoS One
Autori principali: Chen, Jinquan, Ren, Ruxia, Tan, Suiyi, Zhang, Wanyue, Zhang, Xuanxuan, Yu, Fei, Xun, Tianrong, Jiang, Shibo, Liu, Shuwen, Li, Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687630/
https://ncbi.nlm.nih.gov/pubmed/26656730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144522
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