History of the ribosome and the origin of translation

We present a molecular-level model for the origin and evolution of the translation system, using a 3D comparative method. In this model, the ribosome evolved by accretion, recursively adding expansion segments, iteratively growing, subsuming, and freezing the rRNA. Functions of expansion segments in...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Petrov, Anton S., Gulen, Burak, Norris, Ashlyn M., Kovacs, Nicholas A., Bernier, Chad R., Lanier, Kathryn A., Fox, George E., Harvey, Stephen C., Wartell, Roger M., Hud, Nicholas V., Williams, Loren Dean
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687566/
https://ncbi.nlm.nih.gov/pubmed/26621738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509761112
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