Intravitreal Topotecan Inhibits Laser-induced Choroidal Neovascularization in a Rat Model

PURPOSE: A two-phase preclinical study was designed to determine the safe dose of intravitreal topotecan and its inhibitory effect on experimental choroidal neovascularization (CNV) in a rat model. METHODS: In phase I, 42 rats were categorized into 6 groups, 5 of which received intravitreal topoteca...

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Veröffentlicht in:J Ophthalmic Vis Res
Hauptverfasser: Gholipour, Mohammad Ali, Kanavi, Mozhgan Rezaei, Ahmadieh, Hamid, Aldavood, Seyed Javid, Nourinia, Ramin, Hosseini, Seyed Bagher, Daftarian, Narsis, Nashtaei, Ebrahim Mohammad, Tousi, Adib, Safi, Sare
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications & Media Pvt Ltd 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687264/
https://ncbi.nlm.nih.gov/pubmed/26730316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2008-322X.170339
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