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LKB1 and Notch Pathways Interact and Control Biliary Morphogenesis

BACKGROUND: LKB1 is an evolutionary conserved kinase implicated in a wide range of cellular functions including inhibition of cell proliferation, regulation of cell polarity and metabolism. When Lkb1 is inactivated in the liver, glucose homeostasis is perturbed, cellular polarity is affected and cho...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Just, Pierre-Alexandre, Poncy, Alexis, Charawi, Sara, Dahmani, Rajae, Traore, Massiré, Dumontet, Typhanie, Drouet, Valérie, Dumont, Florent, Gilgenkrantz, Hélène, Colnot, Sabine, Terris, Benoit, Coulouarn, Cédric, Lemaigre, Frédéric, Perret, Christine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687046/
https://ncbi.nlm.nih.gov/pubmed/26689699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145400
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