LKB1 and Notch Pathways Interact and Control Biliary Morphogenesis

BACKGROUND: LKB1 is an evolutionary conserved kinase implicated in a wide range of cellular functions including inhibition of cell proliferation, regulation of cell polarity and metabolism. When Lkb1 is inactivated in the liver, glucose homeostasis is perturbed, cellular polarity is affected and cho...

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Udgivet i:PLoS One
Main Authors: Just, Pierre-Alexandre, Poncy, Alexis, Charawi, Sara, Dahmani, Rajae, Traore, Massiré, Dumontet, Typhanie, Drouet, Valérie, Dumont, Florent, Gilgenkrantz, Hélène, Colnot, Sabine, Terris, Benoit, Coulouarn, Cédric, Lemaigre, Frédéric, Perret, Christine
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687046/
https://ncbi.nlm.nih.gov/pubmed/26689699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145400
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