The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes

The transcription factor STAT1 plays a central role in orchestrating responses to various pathogens by activating the transcription of nuclear-encoded genes that mediate the antiviral, the antigrowth, and immune surveillance effects of interferons and other cytokines. In addition to regulating gene...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sisler, Jennifer D., Morgan, Magdalena, Raje, Vidisha, Grande, Rebecca C., Derecka, Marta, Meier, Jeremy, Cantwell, Marc, Szczepanek, Karol, Korzun, William J., Lesnefsky, Edward J., Harris, Thurl E., Croniger, Colleen M., Larner, Andrew C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686975/
https://ncbi.nlm.nih.gov/pubmed/26689548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144444
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