Identification of PCSK9 as a novel serum biomarker for the prenatal diagnosis of neural tube defects using iTRAQ quantitative proteomics

To identify candidate serum molecule biomarkers for the non-invasive early prenatal diagnosis of neural tube defects (NTDs), we employed an iTRAQ-based quantitative proteomic approach to analyze the proteomic changes in serum samples from embryonic day (E) 11 and E13 pregnant rats with spina bifida...

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Udgivet i:Sci Rep
Main Authors: An, Dong, Wei, Xiaowei, Li, Hui, Gu, Hui, Huang, Tianchu, Zhao, Guifeng, Liu, Bo, Wang, Weilin, Chen, Lizhu, Ma, Wei, Zhang, Henan, Cao, Songying, Yuan, Zhengwei
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686913/
https://ncbi.nlm.nih.gov/pubmed/26691006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17559
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