CX3CR1 deficiency promotes muscle repair and regeneration by enhancing macrophage ApoE production

Muscle injury triggers inflammation in which infiltrating mononuclear phagocytes are crucial for tissue regeneration. The interaction of the CCL2/CCR2 and CX3CL1/CX3CR1 chemokine axis that guides phagocyte infiltration is incompletely understood. Here, we show that CX3CR1 deficiency promotes muscle...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Arnold, Ludovic, Perrin, Hélène, de Chanville, Camille Baudesson, Saclier, Marielle, Hermand, Patricia, Poupel, Lucie, Guyon, Elodie, Licata, Fabrice, Carpentier, Wassila, Vilar, José, Mounier, Rémi, Chazaud, Bénédicte, Benhabiles, Nora, Boissonnas, Alexandre, Combadiere, Béhazine, Combadiere, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686853/
https://ncbi.nlm.nih.gov/pubmed/26632270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9972
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