Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

Lung function measures are used in the diagnosis of chronic obstructive pulmonary disease. In 38,199 European ancestry individuals, we studied genome-wide association of forced expiratory volume in 1 s (FEV(1)), forced vital capacity (FVC) and FEV(1)/FVC with 1000 Genomes Project (phase 1)-imputed g...

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Publicado en:Nat Commun
Main Authors: Artigas, María Soler, Wain, Louise V., Miller, Suzanne, Kheirallah, Abdul Kader, Huffman, Jennifer E., Ntalla, Ioanna, Shrine, Nick, Obeidat, Ma'en, Trochet, Holly, McArdle, Wendy L., Alves, Alexessander Couto, Hui, Jennie, Zhao, Jing Hua, Joshi, Peter K., Teumer, Alexander, Albrecht, Eva, Imboden, Medea, Rawal, Rajesh, Lopez, Lorna M., Marten, Jonathan, Enroth, Stefan, Surakka, Ida, Polasek, Ozren, Lyytikäinen, Leo-Pekka, Granell, Raquel, Hysi, Pirro G., Flexeder, Claudia, Mahajan, Anubha, Beilby, John, Bossé, Yohan, Brandsma, Corry-Anke, Campbell, Harry, Gieger, Christian, Gläser, Sven, González, Juan R., Grallert, Harald, Hammond, Chris J., Harris, Sarah E., Hartikainen, Anna-Liisa, Heliövaara, Markku, Henderson, John, Hocking, Lynne, Horikoshi, Momoko, Hutri-Kähönen, Nina, Ingelsson, Erik, Johansson, Åsa, Kemp, John P., Kolcic, Ivana, Kumar, Ashish, Lind, Lars, Melén, Erik, Musk, Arthur W., Navarro, Pau, Nickle, David C., Padmanabhan, Sandosh, Raitakari, Olli T., Ried, Janina S., Ripatti, Samuli, Schulz, Holger, Scott, Robert A., Sin, Don D., Starr, John M., Viñuela, Ana, Völzke, Henry, Wild, Sarah H., Wright, Alan F., Zemunik, Tatijana, Jarvis, Deborah L., Spector, Tim D., Evans, David M., Lehtimäki, Terho, Vitart, Veronique, Kähönen, Mika, Gyllensten, Ulf, Rudan, Igor, Deary, Ian J., Karrasch, Stefan, Probst-Hensch, Nicole M., Heinrich, Joachim, Stubbe, Beate, Wilson, James F., Wareham, Nicholas J., James, Alan L., Morris, Andrew P., Jarvelin, Marjo-Riitta, Hayward, Caroline, Sayers, Ian, Strachan, David P., Hall, Ian P., Tobin, Martin D.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686825/
https://ncbi.nlm.nih.gov/pubmed/26635082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9658
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