LSD1 is essential for oocyte meiotic progression by regulating CDC25B expression in mice

Mammalian oocytes are arrested at prophase I until puberty when hormonal signals induce the resumption of meiosis I and progression to meiosis II. Meiotic progression is controlled by CDK1 activity and is accompanied by dynamic epigenetic changes. Although the signalling pathways regulating CDK1 act...

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Publicado no:Nat Commun
Main Authors: Kim, Jeesun, Singh, Anup Kumar, Takata, Yoko, Lin, Kevin, Shen, Jianjun, Lu, Yue, Kerenyi, Marc A., Orkin, Stuart H., Chen, Taiping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686821/
https://ncbi.nlm.nih.gov/pubmed/26626423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10116
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