Asymmetric ring structure of Vps4 required for ESCRT-III disassembly

The vacuolar protein sorting 4 AAA–ATPase (Vps4) recycles endosomal sorting complexes required for transport (ESCRT-III) polymers from cellular membranes. Here we present a 3.6-Å X-ray structure of ring-shaped Vps4 from Metallosphera sedula (MsVps4), seen as an asymmetric pseudohexamer. Conserved ke...

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Publicat a:Nat Commun
Autors principals: Caillat, Christophe, Macheboeuf, Pauline, Wu, Yuanfei, McCarthy, Andrew A., Boeri-Erba, Elisabetta, Effantin, Gregory, Göttlinger, Heinrich G., Weissenhorn, Winfried, Renesto, Patricia
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686814/
https://ncbi.nlm.nih.gov/pubmed/26632262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9781
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