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NERI: network-medicine based integrative approach for disease gene prioritization by relative importance

BACKGROUND: Complex diseases are characterized as being polygenic and multifactorial, so this poses a challenge regarding the search for genes related to them. With the advent of high-throughput technologies for genome sequencing, gene expression measurements (transcriptome), and protein-protein int...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Simões, Sérgio N, Martins, David C, Pereira, Carlos AB, Hashimoto, Ronaldo F, Brentani, Helena
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686785/
https://ncbi.nlm.nih.gov/pubmed/26696568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S19-S9
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