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Arp2/3-mediated F-actin formation controls regulated exocytosis in vivo

The actin cytoskeleton plays crucial roles in many cellular processes, including regulated secretion. However, the mechanisms controlling F-actin dynamics in this process are largely unknown. Through 3D time-lapse imaging in a secreting organ, we show that F-actin is actively disassembled along the...

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Udgivet i:Nat Commun
Main Authors: Tran, Duy T., Masedunskas, Andrius, Weigert, Roberto, Ten Hagen, Kelly G.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686765/
https://ncbi.nlm.nih.gov/pubmed/26639106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10098
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