Common ataxia telangiectasia mutated haplotypes and risk of breast cancer: a nested case–control study

INTRODUCTION: The ataxia telangiectasia mutated (ATM) gene is a tumor suppressor gene with functions in cell cycle arrest, apoptosis, and repair of DNA double-strand breaks. Based on family studies, women heterozygous for mutations in the ATM gene are reported to have a fourfold to fivefold increase...

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Main Authors: Tamimi, Rulla M, Hankinson, Susan E, Spiegelman, Donna, Kraft, Peter, Colditz, Graham A, Hunter, David J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2004
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC468661/
https://ncbi.nlm.nih.gov/pubmed/15217510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr809
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