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Promoter methylation regulates cyclooxygenase expression in breast cancer

INTRODUCTION: Overexpression of cyclooxygenase (COX-2) is commonly observed in human cancers. In a murine model of metastatic breast cancer, we observed that COX-2 expression and enzyme activity were associated with enhanced tumorigenic and metastatic potential. In contrast to the high COX-2 express...

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Main Authors: Ma, Xinrong, Yang, Qingyuan, Wilson, Keith T, Kundu, Namita, Meltzer, Stephen J, Fulton, Amy M
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC468630/
https://ncbi.nlm.nih.gov/pubmed/15217498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr793
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