Genetic Factors Influencing B-type Natriuretic Peptide-Mediated Production of Cyclic Guanosine Monophosphate and Blood Pressure Effects in Heart Failure Patients

Natriuretic peptides (NPs) represent a critical pathway in heart failure (HF). We explored genetic determinants of pharmacodynamic effects of B-type NP (BNP) and changes in plasma cyclic guanosine monophosphate (cGMP) and blood pressure (BP). HF patients (n=135) received recombinant human BNP (nesir...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Transl Res
Main Authors: Lanfear, David E., Li, Jia, Abbas, Raza, She, Ricoung, Padhukasahasram, Badri, Gupta, Ramesh C., Langholz, David, Tang, W. H. Wilson, Williams, L. Keoki, Sabbah, Hani N., Chow, Sheryl L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686234/
https://ncbi.nlm.nih.gov/pubmed/26589601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-015-9660-2
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