Bone Marrow Derived Myeloid Cells Orchestrate Antiangiogenic Resistance in Glioblastoma through Coordinated Molecular Networks

Glioblastoma (GBM) is a hypervascular and malignant form of brain tumors. Anti-angiogenic therapies (AAT) were used as an adjuvant against VEGF-VEGFR pathway to normalize blood vessels in clinical and preclinical studies, which resulted into marked hypoxia and recruited bone marrow derived cells (BM...

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Veröffentlicht in:Cancer Lett
Hauptverfasser: Achyut, B.R., Shankar, Adarsh, Iskander, ASM, Ara, Roxan, Angara, Kartik, Zeng, Peng, Knight, Robert A., Scicli, Alfonso G, Arbab, Ali S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686232/
https://ncbi.nlm.nih.gov/pubmed/26404753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.09.004
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