Metformin inhibits early stage diethylnitrosamine-induced hepatocarcinogenesis in rats

Antitumor effects of metformin have recently emerged despite its original use for type II diabetes. In the present study, the effects of metformin on the development and recurrence of hepatocellular carcinoma (HCC) were investigated using the diethylnitrosamine (DEN)-induced rat model of HCC. Tumor...

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Bibliographic Details
Published in:Mol Med Rep
Main Authors: JO, WOORI, YU, EUN-SIL, CHANG, MINSUN, PARK, HYUN-KYU, CHOI, HYUN-JI, RYU, JAE-EUN, JANG, SUNGWOONG, LEE, HYO-JU, JANG, JA-JUNE, SON, WOO-CHAN
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2016
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686101/
https://ncbi.nlm.nih.gov/pubmed/26548419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4513
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