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Metformin inhibits early stage diethylnitrosamine-induced hepatocarcinogenesis in rats

Antitumor effects of metformin have recently emerged despite its original use for type II diabetes. In the present study, the effects of metformin on the development and recurrence of hepatocellular carcinoma (HCC) were investigated using the diethylnitrosamine (DEN)-induced rat model of HCC. Tumor...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Med Rep
Hauptverfasser: JO, WOORI, YU, EUN-SIL, CHANG, MINSUN, PARK, HYUN-KYU, CHOI, HYUN-JI, RYU, JAE-EUN, JANG, SUNGWOONG, LEE, HYO-JU, JANG, JA-JUNE, SON, WOO-CHAN
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686101/
https://ncbi.nlm.nih.gov/pubmed/26548419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4513
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