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Multi-transgenic minipig models exhibiting potential for hepatic insulin resistance and pancreatic apoptosis

There are currently no multi-transgenic minipig models of diabetes for the regulation of multiple genes involved in its pathogenesis. The foot and mouth disease virus 2A (F2A)-mediated polycistronic system possesses several advantages, and the present study developed a novel multi-transgenic minipig...

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Dettagli Bibliografici
Pubblicato in:Mol Med Rep
Autori principali: KONG, SIYUAN, RUAN, JINXUE, XIN, LEILEI, FAN, JUNHUA, XIA, JIHAN, LIU, ZHIGUO, MU, YULIAN, YANG, SHULIN, LI, KUI
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686100/
https://ncbi.nlm.nih.gov/pubmed/26648014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4582
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