Genetic susceptibility loci, environmental exposures, and Parkinson’s disease: a case-control study of gene-environment interactions

BACKGROUND: Prior studies causally linked mutations in SNCA, MAPT, and LRRK2 genes with familial parkinsonism. Genome-wide association studies have demonstrated association of single nucleotide polymorphisms (SNPs) in those three genes with sporadic Parkinson’s disease (PD) susceptibility worldwide....

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Detalhes bibliográficos
Publicado no:Parkinsonism Relat Disord
Main Authors: Chung, Sun Ju, Armasu, Sebastian M., Anderson, Kari J., Biernacka, Joanna M., Lesnick, Timothy G., Rider, David N., Cunningham, Julie M., Ahlskog, J. Eric, Frigerio, Roberta, Maraganore, Demetrius M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685949/
https://ncbi.nlm.nih.gov/pubmed/23507417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2013.02.008
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