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Lunatic, Manic and Radical Fringe Each Promote T and B Cell Development
Lunatic, Manic and Radical Fringe (LFNG, MFNG and RFNG) are N-acetylglucosaminyltransferases that modify Notch receptors and regulate Notch signaling. Loss of LFNG affects thymic T cell development and LFNG and MFNG are required for marginal zone (MZ) B cell development. However, roles for MFNG and...
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| Publié dans: | J Immunol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4685716/ https://ncbi.nlm.nih.gov/pubmed/26608918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402421 |
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