γδ Intraepithelial Lymphocyte Migration Limits Transepithelial Pathogen Invasion and Systemic Disease in Mice

BACKGROUND & AIMS: Intraepithelial lymphocytes that express the γδ T cell receptor (γδ IELs) limit pathogen translocation across the intestinal epithelium by unknown mechanisms. We investigated whether γδ IEL migration and interaction with epithelial cells promote mucosal barrier maintenance dur...

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Publicado en:Gastroenterology
Autores principales: Edelblum, Karen L., Singh, Gurminder, Odenwald, Matthew A., Lingaraju, Amulya, El Bissati, Kamal, McLeod, Rima, Sperling, Anne I., Turner, Jerrold R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685713/
https://ncbi.nlm.nih.gov/pubmed/25747597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.02.053
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