The temporal topography of the N-Methyl- N-nitrosourea induced photoreceptor degeneration in mouse retina

Retinitis pigmentosa (RP) is a group of inherited neurodegenerative diseases characterized by the progressive photoreceptors apoptosis. The N-Methyl- N-nitrosourea (MNU) is an alkylating toxicant which could induce photoreceptor apoptosis resembling that of the hereditary RP. However, the detailed p...

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Udgivet i:Sci Rep
Main Authors: Tao, Ye, Chen, Tao, Fang, Wei, Peng, Guanghua, Wang, liqiang, Qin, Limin, Liu, Bei, Fei Huang, Yi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685653/
https://ncbi.nlm.nih.gov/pubmed/26685797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18612
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