Mechanisms of Toll-like receptor 4 endocytosis reveal a common immune-evasion strategy used by pathogenic and commensal bacteria

Microbe-induced receptor trafficking has emerged as an essential means to promote innate immune signal transduction. Upon detection of bacterial lipopolysaccharides (LPS), CD14 induces an inflammatory endocytosis pathway that delivers Toll-like Receptor 4 (TLR4) to endosomes. Although several regula...

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Publicado en:Immunity
Main Authors: Tan, Yunhao, Zanoni, Ivan, Cullen, Thomas W., Goodman, Andrew L., Kagan, Jonathan C.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685471/
https://ncbi.nlm.nih.gov/pubmed/26546281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.10.008
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