NRF2 Regulates HER2 and HER3 Signaling Pathway to Modulate Sensitivity to Targeted Immunotherapies

NF-E2 related factor-2 (NRF2) is an essential transcription factor for multiple genes encoding antioxidants and detoxification enzymes. NRF2 is implicated in promoting cancer therapeutic resistance by its detoxification function and crosstalk with proproliferative pathways. However, the exact mechan...

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Detaylı Bibliyografya
Yayımlandı:Oxid Med Cell Longev
Asıl Yazarlar: Khalil, Hilal S., Langdon, Simon P., Kankia, Ibrahim H., Bown, James, Deeni, Yusuf Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685121/
https://ncbi.nlm.nih.gov/pubmed/26770651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4148791
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