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Transforming growth factor beta upregulates 5-lipoxygenase activity during myeloid cell maturation.

Transforming growth factor beta (TGF beta) increased the arachidonate 5-lipoxygenase (5-LO; EC 1.13.11.34) activity in HL-60 cells induced to granulocytic differentiation by dimethyl sulfoxide. The presence of a factor in human serum that caused a similar increase was recently demonstrated. Several...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Steinhilber, D, Rådmark, O, Samuelsson, B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46851/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8327471/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.5984
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