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Effect of inhibition of interleukin-12/23 by ustekinumab on the expression of leptin and leptin receptor in human THP-1 macrophages

BACKGROUND: Leptin, an adipocyte-derived circulating cytokine that signals nutritional status, may play a role in the development of psoriasis and its associated systemic diseases. Patients with psoriasis have significantly decreased serum leptin levels compared with controls. AIM: To investigate th...

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Detalhes bibliográficos
Publicado no:Clin Exp Dermatol
Main Authors: Voloshyna, I., Mounessa, J., Carsons, S. E., Reiss, A. B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685020/
https://ncbi.nlm.nih.gov/pubmed/26095599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ced.12699
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