The IL-12 response of primary human DC and monocytes to Toxoplasma gondii is stimulated by phagocytosis of live parasites rather than host cell invasion

As a major natural host for Toxoplasma gondii, the mouse is widely used for the study of the immune response to this medically important protozoan parasite. However, murine innate recognition of toxoplasma depends on the interaction of parasite profilin with TLR11 and TLR12, two receptors that are f...

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Gepubliceerd in:J Immunol
Hoofdauteurs: Tosh, Kevin W., Mittereder, Lara, Bonne-Annee, Sandra, Hieny, Sara, Nutman, Thomas B., Singer, Steven M., Sher, Alan, Jankovic, Dragana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685007/
https://ncbi.nlm.nih.gov/pubmed/26597011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501558
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