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Pituitary adenylate cyclase-activating polypeptide (PACAP) disrupts motivation, social interaction, and attention in male Sprague-Dawley rats

BACKGROUND: Severe or prolonged stress can trigger psychiatric illnesses including mood and anxiety disorders. Recent work indicates that pituitary adenylate cyclase-activating polypeptide (PACAP) plays an important role in regulating stress effects. In rodents, exogenous PACAP administration can pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biol Psychiatry
Hauptverfasser: Donahue, Rachel J., Venkataraman, Archana, Carroll, F. Ivy, Meloni, Edward G., Carlezon, William A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684793/
https://ncbi.nlm.nih.gov/pubmed/26229039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.06.013
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