High Glucose/High Lipids Impair Vascular Adiponectin Function via Inhibition of Caveolin-1/AdipoR1 Signalsome Formation

Reduced levels of adiponectin (APN) contribute to cardiovascular injury in the diabetic population. Recent studies demonstrate elevated circulating APN levels are associated with endothelial dysfunction during pre-diabetes, suggesting the development of APN resistance. However, mechanisms leading to...

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Publicat a:Free Radic Biol Med
Autors principals: Liu, Gai-Zhen, Liang, Bin, Lau, Wayne Bond, Wang, Yang, Zhao, Jianli, Li, Rui, Wang, Xi, Yuan, Yuexing, Lopez, Bernard L., Christopher, Theodore A., Xiao, Chuanshi, Ma, Xin-Liang, Wang, Yajing
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684768/
https://ncbi.nlm.nih.gov/pubmed/26453924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.09.005
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