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Expression of the invertebrate sea urchin P16 protein into mammalian MC3T3 osteoblasts transforms and reprograms them into “osteocyte-like” cells

P16 is an acidic phosphoprotein important in both sea urchin embryonic spicule development and transient mineralization during embryogenesis, and syncytium formation and mineralization in mature urchin tooth. Anti-P16 has been used to localize P16 to the syncytial membranes and the calcite mineral....

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Detalhes bibliográficos
Publicado no:J Exp Zool B Mol Dev Evol
Main Authors: Alvares, Keith, Ren, Yinshi, Feng, Jian Q., Veis, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684763/
https://ncbi.nlm.nih.gov/pubmed/26581835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jez.b.22663
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