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Structural interplay between germline and adaptive recognition determines TCR-peptide-MHC cross-reactivity
The T cell receptor - peptide-MHC interface is comprised of conserved and diverse regions, yet the relative contributions of each in shaping T cell recognition remain unclear. We isolated cross-reactive peptides with limited homology, allowing us to compare the structural properties of nine peptides...
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| Publicado no: | Nat Immunol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4684756/ https://ncbi.nlm.nih.gov/pubmed/26523866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3310 |
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