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Systematic coarse-grained modeling of complexation between small interfering RNA and polycations

All-atom molecular dynamics simulations can provide insight into the properties of polymeric gene-delivery carriers by elucidating their interactions and detailed binding patterns with nucleic acids. However, to explore nanoparticle formation through complexation of these polymers and nucleic acids...

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Detalhes bibliográficos
Publicado no:J Chem Phys
Main Authors: Wei, Zonghui, Luijten, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: AIP Publishing LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684570/
https://ncbi.nlm.nih.gov/pubmed/26723631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4937384
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